Abstract: We introduced 50000 Polyodon spathula fries (average 8mm length and 0.006g weight) from Hubei and conducted the technical research for the cultivation of these Large Size Polyodon spathula. Early the fry rearing, the main bait was Cladocera. When the length of the Polyodon spathula reached 50mm, we start trained them with micro-particle formula feed, and about one week later, all Polyodon spathula could ingestion these formula feed. After 48 days cultivation, we had a good cultivation effect: the average length of Polyodon spathula reached 186mm, their weight could be 25.635g, the survival rate also reached 57.8%.