Abstract: In this article,combining with domestic and foreign researches,we reviews the research progress of antihypertensive peptides including the mechanism,preparation method,separation and purification technology,and activity determination means. On this basis,we also gives prospect of the foodborne antihypertensive peptides in medical care development. The paper will provide a basis for further studies of the foodborne antihypertensive peptides. It will be an useful reference for antihypertensive peptide industrial production and marketing,and provide new options for hypertension treatment.