Abstract: Temperature is an important ecological factor affecting the growth and quality of algae.It is of great significance to study the response mechanism of algae to the temperature stress for the expansion of algae culture and cultivation of new varieties.In this paper,the response mechanism of algae to the temperature stress was summarized from the aspects of photosynthetic system,antioxidant system,osmoregulation substances,signal transduction system,heat shock protein and transcription factors.The application and prospect of "omics" and gene editing technology in the study of stress resistance mechanism of algae were introduced.