Abstract: Due to the increasing influence of human production activities, the eutrophication of aquatic ecosystem has aggravated and the red tide closely related to eutrophication have frequently occurred and become a global disaster problem around the world after the period of industrial revolution. The occurrence of red tide will not only damage the marine ecosystem seriously, but also pose a great threat to aquaculture. Although high costs investment with the existing physical and chemical methods can be utilized to control red tide, they may also have negative impacts on the environment. Therefore, to find effective ways to ensure that the occurrence of red tide to be under our control and reduce its adverse effects have become an urgent task. In the previous studies, it stated that some bacteria have the function of inhibiting algae growth and even killing algae, which attracted people's attention gradually. It has shown great potential in the prevention and control of red tide. In recent years, more and more algicidal bacteria have been isolated and identified, which makes a deeper understanding of their algicidal mechanisms. In this paper, the distribution, species and mechanisms of algicidal bacteria were summarized, and the future research direction of marine algicidal bacteria in the field of red tide control was prospected, so as to provide reference and help for developing new red tide control methods.